Details for gene set NCI_IL1-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	NCI_IL1-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.6337172
Normalized Enrichment Score (NES)	-1.5677052
Nominal p-value	0.0
FDR q-value	0.06668101
FWER p-Value	0.691

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	HBP1	2048 2162 21086	207	2.101	0.0158	No
2	KPNB1	20274	617	1.219	0.0094	No
3	RALB	13857	760	1.049	0.0152	No
4	YWHAQ	10369	828	0.997	0.0244	No
5	FKBP1A	2801	880	0.937	0.0337	No
6	YWHAZ	10370	915	0.915	0.0436	No
7	KPNA2	9245	1026	0.826	0.0483	No
8	TICAM2	23440	1095	0.778	0.0546	No
9	MAPKAPK3	19003	1265	0.664	0.0540	No
10	CEBPB	8733	1369	0.609	0.0563	No
11	ARRB2	20806	1508	0.540	0.0558	No
12	MAP3K7	16255	1728	0.446	0.0496	No
13	CASP1	19577	1743	0.440	0.0545	No
14	CASP3	8693	1868	0.395	0.0529	No
15	MAPK8	6459	1918	0.379	0.0551	No
16	YWHAE	20776	1991	0.354	0.0558	No
17	SRF	22961 1597	2181	0.296	0.0493	No
18	MALT1	6274	2207	0.289	0.0517	No
19	MYD88	18970	2257	0.274	0.0526	No
20	CDK4	3424 19859	2258	0.274	0.0561	No
21	CHUK	23665	2349	0.253	0.0545	No
22	PRKCZ	5260	2458	0.222	0.0515	No
23	IRAK1	4916	2512	0.209	0.0513	No
24	TSC2	23090	2549	0.201	0.0519	No
25	CSNK2A1	14797	2669	0.175	0.0477	No
26	IKBKB	4907	2832	0.138	0.0407	No
27	EGR3	4656	3054	0.102	0.0300	No
28	IL1R1	14264 3987	3579	0.059	0.0024	No
29	SLC3A2	23754	3588	0.058	0.0027	No
30	TCF3	17114	3697	0.053	-0.0025	No
31	ELK4	8895 4664 3937	3729	0.051	-0.0035	No
32	IL1B	14431	3930	0.043	-0.0138	No
33	HSPB1	4879	4045	0.039	-0.0195	No
34	FOXP3	9804 5426	4204	0.035	-0.0276	No
35	BCL2	8651 3928 13864 4435 981 4062 13863 4027	4399	0.030	-0.0378	No
36	E2F1	14384	4578	0.027	-0.0471	No
37	IL4	9174	4896	0.022	-0.0640	No
38	FYN	3375 3395 20052	5080	0.020	-0.0737	No
39	IL1A	4915	5169	0.019	-0.0782	No
40	XPO1	4172	5368	0.017	-0.0887	No
41	RAB5A	11310	5448	0.016	-0.0928	No
42	PAK3	9528	5625	0.015	-0.1022	No
43	FBXW11	20926	5630	0.015	-0.1022	No
44	USF1	5832 10260 10261	5657	0.015	-0.1034	No
45	UBE2N	8216 19898	5725	0.014	-0.1069	No
46	SRC	5507	5732	0.014	-0.1070	No
47	IL5	20884 10220	6024	0.012	-0.1226	No
48	PLA2G4A	13809	6112	0.012	-0.1272	No
49	EGR4	24483	6142	0.012	-0.1286	No
50	PPARG	1151 1144 17319	6395	0.010	-0.1422	No
51	CALM1	21184	6700	0.009	-0.1585	No
52	MAPK11	2264 9618 22163	6874	0.008	-0.1678	No
53	IL1R2	14265	6984	0.008	-0.1736	No
54	IL1RN	15096	7041	0.008	-0.1766	No
55	PTGS2	5317 9655	7104	0.007	-0.1798	No
56	GATA3	9004	7432	0.006	-0.1975	No
57	EIF4E	15403 1827 8890	7585	0.006	-0.2057	No
58	PAK1	9527	7592	0.006	-0.2059	No
59	PRKCE	9575	7917	0.005	-0.2234	No
60	PTPRK	5332 20066	8038	0.005	-0.2299	No
61	CD40LG	24330	8298	0.004	-0.2439	No
62	MAP3K7IP1	2193 2171 22419	8369	0.004	-0.2476	No
63	IL2	15354	8581	0.003	-0.2591	No
64	PRKG1	5289	8607	0.003	-0.2604	No
65	PRKCI	9576	9032	0.002	-0.2834	No
66	ATM	2976 19115	9513	0.001	-0.3094	No
67	NFKB2	23810	9535	0.001	-0.3105	No
68	ESR1	20097 4685	9667	0.001	-0.3176	No
69	NR4A1	9099	9752	0.000	-0.3222	No
70	YWHAH	5937 10368	9813	0.000	-0.3254	No
71	LYN	16281	10463	-0.001	-0.3606	No
72	MAPKAPK5	16387	10496	-0.001	-0.3623	No
73	TBX21	20276	10857	-0.002	-0.3818	No
74	YES1	5930	10960	-0.003	-0.3873	No
75	SFN	7060 12062	11240	-0.003	-0.4024	No
76	MAP3K12	6454 11164	11464	-0.004	-0.4145	No
77	CTLA4	14238	11695	-0.005	-0.4269	No
78	NFATC2	5168 2866	11816	-0.005	-0.4334	No
79	IKBKG	2570 2562 4908	11885	-0.005	-0.4370	No
80	MITF	17349	11903	-0.005	-0.4378	No
81	PRKACA	18549 3844	12270	-0.007	-0.4576	No
82	PIK3R1	3170	12501	-0.008	-0.4700	No
83	RIPK2	2528 15935	12516	-0.008	-0.4706	No
84	TH	17548	12533	-0.008	-0.4714	No
85	DUSP16	1004 7699	12672	-0.009	-0.4788	No
86	IL3	20453	12729	-0.009	-0.4817	No
87	CSF2	20454	12730	-0.009	-0.4816	No
88	CSNK1A1	8204	13023	-0.010	-0.4973	No
89	FOSL1	23779	13138	-0.011	-0.5034	No
90	PRKCH	21246	13221	-0.012	-0.5077	No
91	ATF1	8634 4417	13480	-0.013	-0.5215	No
92	RPS6KA5	2076 21005	13507	-0.014	-0.5227	No
93	PIK3CA	9562	13536	-0.014	-0.5241	No
94	ATF2	4418 2759	13658	-0.015	-0.5304	No
95	TNF	23004	13662	-0.015	-0.5304	No
96	GDI1	9012 4770 24297 4769	13827	-0.017	-0.5391	No
97	CAMK4	4473	13955	-0.019	-0.5457	No
98	RNF128	24236 2641	14045	-0.020	-0.5503	No
99	CREB1	3990 8782 4558 4093	14348	-0.026	-0.5664	No
100	FASLG	13789	14495	-0.029	-0.5739	No
101	BCL3	8654	14526	-0.029	-0.5752	No
102	DGKA	3359 19589	14560	-0.030	-0.5766	No
103	ERC1	1013 17021 995 1136	14611	-0.032	-0.5789	No
104	FOS	21202	14780	-0.038	-0.5875	No
105	PRKCQ	2873 2831	14804	-0.038	-0.5883	No
106	POU2F1	5275 3989 4065 4010	15053	-0.048	-0.6011	No
107	DUSP8	9493	15134	-0.052	-0.6048	No
108	CDC25B	14841	15324	-0.063	-0.6142	No
109	TNFRSF1A	1181 10206	15409	-0.069	-0.6179	No
110	ETV1	4688 8925 8924	15435	-0.071	-0.6183	No
111	IFNG	19869	15440	-0.071	-0.6176	No
112	UBE2D3	7253	15448	-0.072	-0.6170	No
113	RELB	17942	15563	-0.083	-0.6222	No
114	FGR	4723	15710	-0.099	-0.6288	No
115	MEF2D	9379	15725	-0.101	-0.6283	No
116	UBE2V1	12381	15795	-0.111	-0.6306	No
117	PPARGC1A	16533	15834	-0.119	-0.6311	No
118	PAK2	10310 5875	15883	-0.126	-0.6321	Yes
119	EIF4EBP1	8891 4661	15908	-0.129	-0.6317	Yes
120	NOD2	6384	15923	-0.131	-0.6308	Yes
121	HCK	14787	15924	-0.131	-0.6291	Yes
122	EGR2	8886	15952	-0.137	-0.6288	Yes
123	MAP3K8	23495	15958	-0.139	-0.6273	Yes
124	RIPK1	5381	15979	-0.143	-0.6265	Yes
125	FKBP8	18587	16082	-0.164	-0.6300	Yes
126	REL	9716	16118	-0.172	-0.6297	Yes
127	YWHAG	16339	16141	-0.177	-0.6286	Yes
128	MEF2C	3204 9378	16157	-0.182	-0.6270	Yes
129	RPS6KA4	23804	16167	-0.184	-0.6252	Yes
130	PTPN1	5325	16237	-0.200	-0.6263	Yes
131	CALM2	8681	16243	-0.203	-0.6240	Yes
132	LCK	15746	16281	-0.210	-0.6233	Yes
133	CYLD	18532	16309	-0.218	-0.6219	Yes
134	YWHAB	14744	16465	-0.265	-0.6269	Yes
135	MAP2K3	20856	16576	-0.300	-0.6290	Yes
136	RAC1	16302	16592	-0.304	-0.6259	Yes
137	IRAK4	22379 11185	16691	-0.337	-0.6269	Yes
138	RALA	21541	16794	-0.371	-0.6277	Yes
139	MAP2K4	20405	16842	-0.384	-0.6253	Yes
140	CALM3	8682	16860	-0.390	-0.6212	Yes
141	MAP2K6	20614 1414	16879	-0.397	-0.6170	Yes
142	RAF1	17035	16923	-0.414	-0.6140	Yes
143	MKNK1	2504	16970	-0.431	-0.6110	Yes
144	IRAK3	19617	17005	-0.445	-0.6071	Yes
145	PRKCD	21897	17066	-0.470	-0.6043	Yes
146	DDIT3	19857	17095	-0.485	-0.5996	Yes
147	PRKCA	20174	17118	-0.497	-0.5943	Yes
148	JUNB	9201	17155	-0.511	-0.5897	Yes
149	BIRC2	4397 4398	17163	-0.514	-0.5835	Yes
150	MAPK14	23313	17215	-0.531	-0.5794	Yes
151	PIM1	23308	17294	-0.572	-0.5762	Yes
152	BAD	24000	17315	-0.582	-0.5698	Yes
153	GSK3B	22761	17375	-0.618	-0.5651	Yes
154	MAPK3	6458 11170	17396	-0.634	-0.5580	Yes
155	MEF2A	1201 5089 3492	17426	-0.654	-0.5511	Yes
156	DUSP10	4003 14016	17441	-0.668	-0.5433	Yes
157	JUN	15832	17458	-0.677	-0.5354	Yes
158	IL2RA	4918	17525	-0.716	-0.5298	Yes
159	NFATC3	5169	17539	-0.726	-0.5211	Yes
160	NFKB1	15160	17596	-0.757	-0.5144	Yes
161	MAP3K14	11998	17649	-0.792	-0.5070	Yes
162	TOLLIP	7039 12038	17655	-0.796	-0.4971	Yes
163	RELA	23783	17734	-0.859	-0.4902	Yes
164	SYK	21636	17870	-0.978	-0.4849	Yes
165	BCL10	15397	17878	-0.984	-0.4726	Yes
166	MAP3K7IP2	19827	17902	-1.009	-0.4609	Yes
167	TRAF6	5797 14940	17908	-1.020	-0.4480	Yes
168	ITCH	4928 9185	17926	-1.035	-0.4356	Yes
169	LSP1	18003	17990	-1.095	-0.4249	Yes
170	MAP3K3	20626	17998	-1.103	-0.4111	Yes
171	CBLB	5531 22734	18038	-1.159	-0.3983	Yes
172	TNFAIP3	19810	18051	-1.180	-0.3837	Yes
173	DUSP1	23061	18067	-1.196	-0.3691	Yes
174	IRF4	21679	18103	-1.237	-0.3551	Yes
175	CREBBP	22682 8783	18124	-1.271	-0.3398	Yes
176	SQSTM1	9517	18137	-1.290	-0.3238	Yes
177	NFKBIA	21065	18148	-1.309	-0.3075	Yes
178	SLC9A1	16053	18154	-1.316	-0.2908	Yes
179	CCM2	20950	18223	-1.441	-0.2759	Yes
180	MAPKAPK2	13838	18261	-1.536	-0.2582	Yes
181	MAP3K1	21348	18282	-1.594	-0.2387	Yes
182	MAPK9	1233 20903 1383	18352	-1.775	-0.2196	Yes
183	BLK	3205 21791	18473	-2.331	-0.1961	Yes
184	NFATC1	23398 1999 5167 9455 1985 1957	18532	-2.758	-0.1637	Yes
185	EGR1	23598	18568	-3.340	-0.1225	Yes
186	TP53	20822	18582	-3.909	-0.0729	Yes
187	RAN	5356 9691	18611	-5.793	0.0003	Yes